Premier League giant Manchester United will play Belgian club Anderlecht in the Europa League quarterfinals.
United's first ever European game came against Anderlecht in 1956, and United won 2-0 in the European Cup preliminary rounds.
Their 10-0 victory in the second leg remains United's record win.
The two clubs met again in the 1968 European Cup second round, when United progressed 4-3 on aggregate.
Anderlecht are at the top of the Belgian First Division on goal difference and reached this stage of the Europa League by beating Apoel Nicosia 1-0 home and away in the round of 16.
United boss Jose Mourinho had previously suggested he would prioritise winning the Europa League which would guarantee Champions League qualification
Should Mourinho's side win the competition this season, they would become only the fifth club to win all three major European trophies, after Ajax, Bayern Munich, Chelsea and Juventus.
Spanish side Celta Vigo faces the other Belgian side in the final eight of the tournament, Genk.
Former winners of the competition, Dutch side, Ajax and German side Schalke 04 will play each other.
French Lique one side Lyon take on Turkish giant Besiktas in a tie involving two sides that entered the tournament after finishing third in their Champions League groups.